Rate control was more cost effective than rhythm control in persistent atrial fibrillation

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Rate control was more cost-effective than rhythm control in persistent atrial fibrillation.

Intervention: rate control (n = 256) or rhythm control (n = 266). Rate control included use of digitalis, a non-dihydropyridine calcium channel blocker, and a b blocker, alone or in combination. Target resting heart rate was ,100 beats/minute. Patients in the rhythm control group received serial electrical cardioversion and serial antiarrhythmic drugs using sotalol, 160– 320 mg/day, as the firs...

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Rhythm or rate control in persistent atrial fibrillation

Selecting appropriate treatment strategies for patients with persistent atrial fibrillation has often proved to be a quandary. Foregoing any debate on anticoagulant therapy, the remaining issue is whether the ultimate goal should be achieving and maintaining sinus rhythm or simply controlling the ventricular response during ongoing atrial fibrillation. Since atrial fibrillation affects 5% of th...

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Cost-effectiveness of rhythm versus rate control in atrial fibrillation.

BACKGROUND Atrial fibrillation is the most common type of sustained cardiac arrhythmia, but recent trials have identified no clear advantage of rhythm control over rate control. Consequently, economic factors often play a role in guiding treatment selection. OBJECTIVE To estimate the cost-effectiveness of rhythm-control versus rate-control strategies for atrial fibrillation in the Atrial Fibr...

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Rate versus rhythm control in atrial fibrillation.

OBJECTIVE To determine whether rate control is a viable initial treatment approach in persistent atrial fibrillation (AF) through the evaluation of recently completed trials comparing rate and rhythm control. DATA SOURCES Biomedical literature was obtained through MEDLINE (1966-December 2003) and the Iowa database. STUDY SELECTION AND DATA EXTRACTION Articles identified from the biomedical ...

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A comparison of rate control and rhythm control in patients with recurrent persistent atrial fibrillation.

BACKGROUND Maintenance of sinus rhythm is the main therapeutic goal in patients with atrial fibrillation. However, recurrences of atrial fibrillation and side effects of antiarrhythmic drugs offset the benefits of sinus rhythm. We hypothesized that ventricular rate control is not inferior to the maintenance of sinus rhythm for the treatment of atrial fibrillation. METHODS We randomly assigned...

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ژورنال

عنوان ژورنال: Evidence-Based Medicine

سال: 2005

ISSN: 1356-5524

DOI: 10.1136/ebm.10.2.59